Ingelvac MycoFLEX suspension for injection for pigs. 2. root-ingelvacmycoflex- fr-vbloqa/p1/1b-spc-pl/terney.info Page 2 of Ingelvac MycoFLEX suspension for injection for pigs. 2. QUALITATIVE AND QUANTITATIVE COMPOSITION. Inactivated Mycoplasma hyopneumoniae, J Strain. Fold PDF 4 hal. 29Jun Ingelvac . MycoFLEX. Insert. /8” x /4”. /8” x /8”. 29Jun15 hal. BLACK.
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PDF Rev Level 2 lsh. 17Jan Ingelvac MycoFLEX. Insert. /8” x /4”. /8” x /8”. 17Jan14 lsh. BLACK. Ingelvac® MycoFLEX™. Mycoplasma hyopneumoniae bacterin. Boehringer Ingelheim (Canada) Ltd. Vetmedica Division. South Service Road. Burlington. The FLEXcombo® package contains one bottle of Ingelvac. CircoFLEX® and one bottle of. Ingelvac MycoFLEX®. The Ingelvac. MycoFLEX® is supplied in a.
There were no macroscopic lung lesions in the negative control group. The average lymphohistiocytic infiltration score was lower in group V1 2. The V1 group had the highest average percentage of air in the lung tissue The results from the IF testing that was used to semi-quantitatively assess the load of M. All pigs of the negative control group were negative for IF staining.
Lower numbers of organisms were detected in groups V1 and V2 Several bacteria were isolated from BAL fluid.
The bacteriological culture remained negative for all pigs in the negative control group. Serology The serological results for M. None of the pigs in the PCG had seroconverted to M. All pigs in the negative control group were serologically negative at all time-points. Table 4 Percentage of seropositive pigs in the different groups at different time-points during the trial Full size table Discussion The present experimental trial investigated whether the efficacy of one-shot vaccination is influenced by the weaning process.
Differences between V1 vaccination three days before weaning , V2 vaccination at weaning and the PCG no vacination were small and mostly statistically not significant, except for the microscopic lung lesions, which were lower in V1. Apart from the transport related to the weaning process, the piglets in the present study were also transported to the experimental facilities, a trip that lasted anywhere from one-half to two hours.
In fact, age- and site-segregated pork production is a complex process that involves movement of the piglets from the farrowing house to the nursery facilities, which are situated in different locations [ 17 ]. It can be expected, though, that the stress imposed on the piglets in our study may have been greater than when the piglets remain on the same site and are not transported e.
Vaccination at the moment of weaning, when the piglets are being handled anyway, is a common practice, as it can be implemented easily in the daily management of a pig herd. The pigs of V1 were vaccinated three days before weaning.
A difference of three days between the two vaccination groups most probably allowed sufficient time for the development of the first and most critical steps of the immune response prior to the stress of weaning [ 20 ]. At the same time, too great a difference in age at vaccination was avoided between the piglets in the V1 and V2 groups. In this sense, the two vaccination schemes are relevant for the situation in many pig herds.
The experimental infection model used for M. Challenge infection proved to be successful since the vast majority of the infected pigs had positive qPCR values, exhibited the presence of Mycoplasma-like macroscopic lung lesions at necropsy and were positive for IF staining.
However, the macroscopic lung lesions observed in the present trial were milder compared to trials that had been previously conducted using the same inoculation dose of M. The precise reasons for this difference are not known. Based on the macroscopic lung lesion scores, serology, qPCR testing and IF staining, all the pigs in the negative control group were negative for M. There were no significant differences in ADG between the groups. This is mainly due to the high standard deviations observed and the limited numbers of pigs.
ADG was measured, but it was not considered an important parameter for this experimental study.
In vaccination trials under field conditions however, in which many more animals can be included, ADG is an important parameter. Group V1 had the lowest numbers of macroscopic and histopathological lung lesions, and the lowest IF scores when compared to groups V2 and PCG. There were no post-injection treatment MO. However, tail base proximity for width x A total of 8.
Vetmedica Inc. The authors were blind to injection treatments until the recommended for use as a practical on-farm pig behavioral data had been collected and statistical models were welfare assessment measure.
Nursery pen image capturing device: The nursery pen image capturing device location was free-standing across the alleyway from each pen gate Figure One. Schematic of the digital image capturing Measures device Behavior and snout and tail base proximity: Data were collected h prior to injection to establish pre-injection baseline values and a second time 6-h after injection to establish post-injection values.
There was a possibility to collect total snout and tail base anatomical data values. The ruler tool was calibrated using a length ratio 6.
Changhoon Park and Ikjae Kang contributed equally to this work. Received Apr 15; Accepted Nov Abstract The objective of this study was to compare the efficacy of 2 different commercial Mycoplasma hyopneumoniae vaccines and porcine reproductive and respiratory syndrome virus PRRSV vaccines in regard to growth performance, microbiological and immunological analyses, and pathological observation from wean to finish d of age.
Pigs were administered M. The present study demonstrated that the single-dose vaccination regimen for M. Traduit par Docteur Serge Messier Introduction Mycoplasma hyopneumoniae is the etiological pathogen of enzootic pneumonia, which is characterized by a chronic, nonproductive cough 1.
Infection of M. Porcine reproductive and respiratory syndrome PRRS virus PRRSV is an enveloped, single-stranded, positive-sense RNA virus belonging to the Arteriviridae family in the order Nidovirales 3 that can cause reproductive problems in sows and respiratory problems in growing pigs 4.
In pigs, respiratory disease is multifactorial and complex and is caused by sequential or concurrent infections with several viral or bacterial pathogens; therefore, the name porcine respiratory disease complex PRDC is used to describe this disease 5 , 6.
The economic impact of PRDC is tremendous, mainly due to decreased fattening performance and the cost of medication 7 , 8.
Currently, the use of antibiotics for controlling PRDC is limited due to increased risk of antimicrobial resistance and residue in carcasses 9.
Therefore, vaccinations are of prime importance and are routinely applied worldwide. Since coinfection with M. Joseph, Missouri, USA was first licensed for worldwide use in A comparison of both single-dose M. The objective of the present study was to compare the efficacy of 2 commercial single-dose M. Materials and methods Commercial vaccines Two types of commercial M.