Part of the National Medical Series (NMS), this book provides a quick review of clinical Psychiatry with USMLE-style (vignette) questions for self-study and. Part of the National Medical Series NMS, this book provides a quick review of clinical Psychiatry with USMLE-style vignette questions for. Treatment in Psychiatry begins with a hypothetical case illustrating a problem in current clinical Despite its declining frequency, however, NMS remains a.
|Language:||English, Spanish, Arabic|
|Distribution:||Free* [*Registration Required]|
NMS has a relative high mortality outcome compared to common psychiatric conditions. Psychotropic medications such as the typical and atypical4,5. This is great core text for your Psychiatry Clerkship. It also covers a lot of information that is useful for your Internal Medicine, Family Medicine, Pediatrics and. Clues to an NMS diagnosis include a recent diagnosis of a psychotic disorder and inpatient psychiatric hospitaliza- tion. This information, along.
Fatal hyperpyrexia during chlorpromazine therapy.
J Clin Exp Psychopathol. A non-phenothiazine and non-reserpine major neuroleptic, haloperidol, in the treatment of psychoses in French. Ann Med Psychol Paris. Neuroleptic malignant syndrome: a review.
Severe and uncommon involuntary movement disorders due to psychotropic drugs. Frequency and presentation of neuroleptic malignant syndrome in a large psychiatric-hospital. Am J Psychiatry. Symptoms of neuroleptic malignant syndrome in 82 consecutive inpatients. Neuroleptic malignant syndrome. Psychopharmacol Bull. Buckley PF, Hutchinson M. J Neurol Neurosurg Psychiatry. Atypical antipsychotics and newer antidepressants.
Emerg Med Clin North Am. Br J Anaesth. The evaluation and management of patients with neuroleptic malignant syndrome. Neurologic Clin. Med Clin North Am. Serum iron and neuroleptic malignant syndrome. A case of neuroleptic malignant syndrome accompanied to an atypical antipsychotic agent: risperidone.
Apparent neuroleptic malignant syndrome with clozapine and lithium. J Nervous Mental Dis. A typical neuroleptic malignant syndrome with quetiapine a case report and review of the literature. J Clin Psychopharmacol. Kantrowitz JT, Citrome L. Olanzapine: review of safety Expert Opinion Drug Safety. Established risk factors are summarized with an emphasis on pharmacological and environmental causes.
Leading theories about the etiopathology of NMS are discussed, including the potential contribution of the impact of dopamine receptor blockade and musculoskeletal fiber toxicity. A clinical perspective is provided whereby the clinical presentation and phenomenology of NMS is detailed, while the diagnosis of NMS and its differential is expounded.
Current therapeutic strategies are outlined and the role for both pharmacological and non-pharmacological treatment strategies in alleviating the symptoms of NMS are discussed.
Keywords: Antipsychotic, drug side-effects, neuroleptic malignant syndrome, psychopharmacology. Initially described by Delay and colleagues in [ 1 ], shortly after the introduction of antipsychotic medications to psychiatry, its diagnosis represents a significant challenge for clinicians.
In addition, there are many aspects regarding its epidemiology, etiopathology and nosology that remain controversial. The present work aims to review current literature about NMS from a clinically-oriented perspective.
Prevalence estimates range from 0. The pathogenesis of NMS is mainly attributable to dopamine blockade, 7 - 9 and dysregulated sympathetic system hyperactivity is responsible for most features of NMS. NMS can occur in patients given atypical antipsychotics and resembles classical NMS with typical antipsychotics. He first presented to our hospital in June with four months history of sleep disturbances, being preoccupied, hallucinatory behavior and persecutory thought contents.
There was no significant past psychiatric history, and the patient had no physical illnesses at this time. He was on thioridazine 25 mg three times a day for eight to ten days from a private doctor.
The patient used to drink one or two pegs of country liquor occasionally but was totally abstinent for the last seven to eight months. No depressive features were noted.
He was prescribed trifluperazine 5 mg twice a day along with chlordiazepoxide 25 mg at night to which he developed extrapyramidal symptoms EPS bradykinesia, mild tremors and increase in salivation. Trihexyphenidyl 2 mg per day was added. Later, the patient presented with anergia and anhedonia but no mood disturbances were reported. Fluoxetine was added two months later September