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Las Escrituras. Instead, it is a blood substitute, also known as an HBOC, for hemoglobin-based oxygen carrier. The solution is made from purified bovine -- meaning cow -- hemoglobin, which is the molecule in blood that carries oxygen to the tissues.
Hemopure has a roller-coaster history full of intrigue.
Hemopure is not approved for use in the United States, although it is in at least one country, South Africa. Before being purchased by OPK Biotech, a private company, Hemopure was developed and produced by a public corporation also in Cambridge called Biopure. The corporation manufactured an effective blood substitute that can be used in dogs. Biopure rode a wave of investor success from through on the prospect that it would produce a safe, synthetic blood substitute that not only could help reduce the worldwide shortage of human blood, but also could be stored for long periods of time, making it useful in remote areas as well as on battlefronts.
But Hemopure languished in human clinical trials. Authorities later alleged that company officials had filed misleading reports about the status of its product to the Securities and Exchange Commission, leading to indictments of top company executives.
In , a year before the company filed for bankruptcy and its assets were sold to OPK Biotech, a medical review of blood substitutes that included Hemopure pointed out dangers, including increased risk of death by heart attack.
Richart said the blood substitute needs to be given in a slow and controlled manner.
C, which needed to give a special compassionate care dispensation for the Hemopure to be used in the Unites States. Then KU was on the phone with OPK in Cambridge, where the city was still reeling less than 12 hours after two bombs killed three people and injured many more.
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